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Pharmaceutical Process Design II: Pharmaceutical Unit Operations - (Spring 2008)

The course provides an introduction to the essential operations used in the manufacture of pharmaceutical products. The course discusses the pharmaceutical product life-cycle, variability, testing, and specifications of pharmaceutical ingredients. Unit operations including blending, granulation, fluidized bed operations, milling, capsule filling, compaction, tablet coating and other processes will be addressed. Students learn to recognize how the output of one process is the input to the next process, and how deviations can cascade along the production sequence until they cause process failures. The course emphasizes design, scale-up, trouble-shooting, and optimization.