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The Doctoral
Training Program in Pharmaceutical Engineering at Rutgers, The State
University of New Jersey was established in 1995. It is one of a
select group of such programs throughout the country funded by the
National Science Foundation. It is located on the Busch Campus in
Piscataway, NJ, where it is an integral part of the activities of
the Department of Chemical and Biochemical Engineering, College
of Pharmacy, Departments of Ceramics, Industrial Engineering, and
Mechanical Engineering.
One of the
greatest challenges of the pharmaceutical industry is to design
and optimize manufacturing processes for the efficient and safe
production of pharmaceutical products. To achieve this, a new type
of professionals must be trained who are fluent in the language
of basic chemical process engineering principles and are knowledgeable
in the engineering science and unit operations of pharmaceutical
manufacturing such as blending, crystallization, compaction, sampling
and granulation. The program's purpose is to provide predoctoral
students with integrated, interdisciplinary didactic and research
training in pharmaceutical engineering. Students are trained to
become professionals who are well-educated within a single discipline,
and who also have the cross-disciplinary skills required to support
the needs of the industrial and academic pharmaceutical sectors.
The research
programs of the training faculty cover a broad spectrum of problems
in pharmaceutical manufacturing. The majority of projects fall under
the following research thrusts:
Blending:
equipment design; size and shape segregation; time-of-mix studies;
content uniformity; numerical modeling of powder flow.
Compaction: compactor simulator studies; material
properties; modeling of compaction processes; tool design; tablet
formulation; dissolution profiles.
Crystallization: thermodynamics of nucleation;
growth kinetics; impact of mixing on particle size distribution;
population balance modeling; on-line monitoring.
Granulation: melt granulation; high shear granulators.
Milling: ball mills; high shear mills.
Sampling:
content uniformity; design of sampling schemes; infra-red
monitoring; image analysis of particulates.
The training
program is in the heart of the largest concentration of
pharmaceutical industries in the country. Industrial partners participate
in the programs in the following ways:
Internships: Students spend at least one summer
as an intern working in one of the partner's laboratories. This
serves to familiarize the students with practical problems encountered
by industry.
Dissertation
Research: Industrial representatives will be invited
to serve on doctoral dissertation committee. This serves to promote
interactions between industrial faculty and students.
Seminars and Courses: Industrial investigators
participate in seminar and courses. This allows the students to
gain insights into the complexities involved in pharmaceutical technological
development.
For additional
information regarding this program go to:
Pharmaceutical
Engineering and Particle Processing Homepage


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